Nystatin: What it is and when to use it
Nystatin is a time-tested antifungal medicine that fights Candida infections on skin, in the mouth, and in the gut. It’s not a pill you usually swallow for systemic infections—most of the time it stays local: creams, powders, ointments for skin and a liquid (suspension) for mouth or intestinal yeast. Doctors pick nystatin when the infection is localized and you want a medicine that acts right where the fungus lives.
Easy, practical ways to use Nystatin
If you have a skin or diaper rash, clean and dry the area first. Apply a thin layer of nystatin cream or ointment to the affected skin and a bit around it, usually two to four times daily or as your clinician tells you. For skin folds and moist areas, keep the skin as dry as possible before application—fungus loves moisture.
For mouth infections (oral thrush), you’ll get a liquid suspension. Swish the prescribed amount around the mouth so it coats the infected spots, then either spit or swallow based on your doctor’s instructions. Follow the full course even if symptoms improve quickly—stopping early lets the fungus come back.
Side effects, precautions, and when to call your doctor
Most people tolerate nystatin well because it’s poorly absorbed into the bloodstream. The common side effects are local: mild burning, itching, or skin irritation where you put it. If you use the oral form you might get a little stomach upset or nausea.
Allergic reactions are rare but possible. If you notice swelling of the face, lips, tongue, trouble breathing, or a sudden rash, stop the medicine and seek emergency care. Also call your prescriber if the infection hasn’t improved in 7–14 days or if it’s spreading rapidly—sometimes a different treatment is needed.
Nystatin rarely interacts with other drugs because it doesn’t reach high blood levels. Still, tell your doctor about other medications, pregnancy, or breastfeeding—your provider will confirm it’s the right choice for you.
Storage is simple: keep creams and liquids at room temperature away from heat and direct sunlight. Throw away expired medicine. For the best results, stick to the dosing schedule, keep the infected area clean and dry, and finish the full treatment even if you feel better.
Nystatin is a solid, low-risk option for common Candida issues when used correctly. If you’re unsure whether your problem is fungal or something else, or if you have repeated infections, ask a clinician—sometimes lab testing or a different treatment is needed.
